In vitro activity of OLEOZON against etiological agents of skin infections

Authors

  • Irene Lezcano Centro de Investigaciones del Ozono
  • Jesús Molerio Centro de Investigaciones del Ozono
  • Magaly Gómez Centro de Investigaciones del Ozono
  • Rolando Contreras Centro Nacional de Investigaciones Científicas
  • Gloria Roura Centro Nacional de Investigaciones Científicas,
  • Wilfredo Díaz Centro Nacional de Investigaciones Científicas

Abstract

Pyogenic skin infection are produced in 90 % of cases by Staphy-lococcus aureus and Streptococcus pyogenes; Pseudomonas aeruginosa and Es-cherichia coli can participate as secondary agents. OLEOZON has antimicro-bial effects against different microorganisms. In the present study, the antibac-terial activity of OLEOZON against Staphylococcus aureus, Streptococcus pyogenes, Pseudomonas aeruginosa and Escherichia coli clinical isolates and Staphylococcus aureus ATCC 29213, Pseudomonas aeruginosa ATCC 27853 and Escherichia coli ATCC 25922 was examined. Susceptibility tests, Minimal In-hibitory Concentration and Minimal Bactericidal Concentration, were performed by agar dilution and macrodilution techniques based on NCCLS 1992, 1993; as well as bioactivity tests by microcalorimetry technique were performed. The results showed the powerful antimicrobial activity of OLEOZON against the bacterial strains analyzed in this study. It made possible to recommend other experiments in order to establish the effective dose and the appropiate thera-peutical procedure for this disease.

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Published

2022-11-14

How to Cite

Lezcano, I. ., Molerio, J., Gómez, M. ., Contreras, R. ., Roura, G. ., & Díaz, W. . (2022). In vitro activity of OLEOZON against etiological agents of skin infections. NATIONAL CENTER FOR SCIENTIFIC RESEARCH (CENIC) BIOLOGICAL SCIENCES JOURNAL, 29(3), 209-214. Retrieved from https://revista.cnic.edu.cu/index.php/RevBiol/article/view/2749

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Research articles