MECHANISMS THAT SUPPORT THE EFFECTIVENESS OF D-004, LIPID EXTRACT FROM THE FRUIT OF LA PALMA REAL, IN EXPERIMENTAL MODELS OF PROSTATIC HYPERPLASIA

Authors

  • Yohani Pérez Guerra

Abstract

Benign prostatic hyperplasia (BPH), a common disease in men from 50 years of age, produces various symptoms of the lower urinary tract (UTS) that affect the quality of life. Its multifactorial etiology fundamentally involves the increase in the conversion of testosterone (T) to dihydrotestosterone (DHT) by the action of 5α-reductase prostate, which triggers events that lead to an increase in the size of the prostate (static component of BPH) and increased smooth muscle tone of the bladder and prostate (dynamic component) regulated by adrenoreceptors (ADR) -α1. Pharmacological treatment of BPH includes 5α-reductase inhibitors, antagonists of ADR-α1, its combined therapy and herbal medicine [mainly lipid extracts from palm fruits saw palmetto (Serenoa repens) (ELSP)].  

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Published

2020-11-03

How to Cite

Pérez Guerra, Y. . (2020). MECHANISMS THAT SUPPORT THE EFFECTIVENESS OF D-004, LIPID EXTRACT FROM THE FRUIT OF LA PALMA REAL, IN EXPERIMENTAL MODELS OF PROSTATIC HYPERPLASIA. NATIONAL CENTER FOR SCIENTIFIC RESEARCH (CENIC) BIOLOGICAL SCIENCES JOURNAL, 41(1), 001-002. Retrieved from https://revista.cnic.edu.cu/index.php/RevBiol/article/view/611